YMC-Triart Bio C4 20 mm x 2.1 mm x 5 um

Hybrid Silica ODS

YMC-Triart Bio C4 is a novel, organic/inorganic hybrid silica derivatized with C4 (L26 USP designation) based on wide-pore (300Å) particles. This new stationary phase is designed for HPLC and UHPLC separations of proteins and oligonucleotides, and is particularly useful for intact antibody analyses run at high temperatures. Triart Bio C4 is well-suited for high-sensitivity analysis using mass spec-friendly mobile phases containing formic acid and/or TFA. As with all Triart products, chromatographers enjoy wide temperature and pH ranges (up to 90°C at pH 1-7, and 50°C at pH 7-10), allowing these parameters to be used as tools for optimizing separation conditions, without having to worry about stationary phase durability.

Triart Hybrid Advantages

The core material for all of the YMC-Triart products – the particle – is inspired by YMC’s flow chemistry technology. Inherent in YMC’s process is a high level of temperature and particle formation control. As a result, Triart particles are consistent, reproducible, and scalable across many particle sizes. The hybrid Triart particles produce a material that is highly resilient and robust when used at extreme pH and elevated temperature. In addition, these particles are very stable under mechanical stress such as high pressure.

• Triart Bio C4 is a wide-pore 300Å hybrid silica phase designed for biomolecule separations
• Suitable for the separation of intact antibodies under high temperatures (up to 90°C)
• Available in UHPLC and HPLC columns packed with 1.9, 3, or 5µm particles, offering a wide pH range of 1-10.
• Compatible with 100% aqueous mobile phases.
• Proprietary endcapping makes for excellent peak shapes of proteins when using MS-friendly mobile phases containing formic acid and TFA.
• The chemical stability of the Triart material combines with the inherent mechanical durability of the particles themselves to contribute to long column lifetime.
• Rigorous manufacturing controls result in legendary YMC column-to-column and lot-to-lot reproducibility.
• Triart Bio C4 is available in packed columns of various dimensions.

YMC-Triart columns are well-suited to a variety of applications in pharmaceutical and chemical laboratories. YMC-Triart’s performance in wide-ranging conditions arguably makes it the ideal reversed-phase column choice.