Newcrom A is a mixed-mode analytical column with negatively-charged acidic ion-pairing groups at the terminal end of long ligand chains.
Newcrom A offers the following advantages:
– Improved retention of weak basic compounds through a cation-exchange mechanism.
– Enhanced retention of multi-charged compounds.
– Separation of acids by an ion-exclusion mechanism.
– Retention of neutral compounds via a reverse-phase mechanism.
– Low buffer concentration required to generate efficient ion-exchange.
– Compatibility with typical mobile phases for LC-MS and preparative chromatography.
