Newcrom BH is a mixed-mode analytical column with positively-charged basic ion-pairing groups at the terminal end of short ligand chains.
Newcrom BH offers the following advantages:
– Improved retention of weak acidic compounds through an anion-exchange mechanism.
– Enhanced retention of multi-charged compounds.
– Separation of bases by an ion-exclusion mechanism.
– Retention of neutral compounds via a reverse-phase mechanism.
– Low buffer concentration required to generate efficient ion-exchange.
– Compatibility with typical mobile phases for LC-MS and preparative chromatography.