YMC-Pack CN 75 mm x 30.0 mm x 5 um

YMC SKU: CN12S05-L530WT

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Useful in Both Normal-Phase and Reversed-Phase Modes

YMC-Pack CN can be used for both normal-phase and reversed-phase analyses due to the medium polarity of the cyanopropyl phase bonded to the silica base particle.  It can be used in normal-phase with low-polarity mobile phases such as hexane, or in reversed-phase with highly-polar mobile phases such as methanol and water.  YMC-Pack CN can be useful for shortening analysis time in situations where retention is substantial using C18 or C8, or when separation optimization is difficult.

In reversed-phase mode, cyano columns are the most polar and least retentive of all reversed-phase packings.  Extremely hydrophobic compounds which do not elute in standard C18 and C8 packings can be retained using typical reversed-phase eluents.  In addition, the unique nitrile chemistry provides different selectivity from both phenyl and standard aliphatic (C18, C8, and C4) reversed-phase packings.  Large pore-size 300Å packing materials are also available for the analysis of biomolecules in order to utilize this unique selectivity.

In normal-phase mode, cyano is a bonded phase that can be used as an alternative to silica.  Bonded normal-phase columns have the advantage of faster equilibration and more uniform surface activity compared to bare silica gel.

To extend column lifetime, continued switching back and forth between normal- and reversed-phase solvents should be avoided.

  • Useful in both normal- and reversed-phase applications
  • Stable, high coverage, monomerically-bonded phase
  • Fully endcapped
  • Alternative selectivity
  • Available in 300Å for biomolecule analysis
Chemistry: Cyanopropyl (CN)
Length: 75 mm
Internal Diameter: 30 mm
Particle size: 5.0 um
Pore size: 120Å
Surface Area: 330 m2/g
Carbon Load: 7%
Endcapped: Yes
Max. pressure: 250 bar
pH range: 2.0-7.5
MaxTemp: 50⁰C
USP Class: L10
Brand: YMC-Pack CN
Manufacturer: YMC (Nhật)