Ultisil LP-C8 column consists of two very bulky hydrophobic protective groups to prevent siloxane bond from hydrolysis at low pH condition. So Ultisil LP column is extremely stable in very low pH mobile phase and at high temperature, even at the lowest pH of 1.0. LP-C8 is resistant to 100% aqueous phase and it is less retentive than LP-C18 phase.
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